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How to Avoid Getting Sick on a Plane During Flu Season

Key takeaways

  • Maintain hand hygiene with soap and alcohol-based sanitizer containing at least 60% alcohol, and avoid touching your face since germs only cause infection when they reach your nose, mouth, or eyes.
  • Window seats reduce transmission risk compared to aisle seats, and keeping your overhead air vent directed downward creates a protective cone against airborne germs.
  • Airplane cabins maintain only 10-20% humidity; drink eight ounces of water per hour to keep your mucous membranes resilient against viruses.
  • Get vaccinated with flu shots, COVID-19 boosters, and RSV vaccines before flying, and take 1,000 milligrams of vitamin C daily during stressful travel to reduce infection risk.

Respiratory illnesses are circulating at high levels this season. Currently, a blend of COVID-19, influenza, and respiratory syncytial virus (RSV) is spreading, alongside other pathogens including norovirus and bacterial infections like E. coli. According to Dr. Waleed Javaid, an epidemiologist and professor of medicine at West Virginia University, “As we enter the colder months and holiday gatherings, respiratory infections are on the rise due to increased close contact and indoor activities.”

Flying involves hours of close proximity with hundreds of strangers in a confined space where respiratory viruses spread readily. Years of pandemic precautions revealed effective strategies for staying healthy while traveling. Dr. Taz Bhatia, a board-certified integrative medicine physician, explains: “COVID taught us the importance of hand hygiene and boosting immunity through lifestyle practices.” The same measures that reduced COVID transmission will protect you from seasonal flu and other respiratory viruses.

Mask Protection

Though mask mandates on flights have ended, wearing one offers measurable defense. A 2020 study by the U.S. Department of Defense found the risk of COVID-19 transmission on planes was “extremely unlikely” when masks were worn. Masks also block other respiratory viruses transmitted through the air, including influenza. The Centers for Disease Control and Prevention currently recommends masks for travelers showing fever or respiratory symptoms, and for those seated near symptomatic passengers when the patient cannot tolerate wearing a mask.

How to Avoid Getting Sick on a Plane During Flu Season

Hand Hygiene Practices

Washing and Sanitizing

Dr. Nicholas Testa, California regional chief medical officer at CommonSpirit Health, emphasizes the fundamentals: “Keep your hands clean with either soap and water or an alcohol-based hand sanitizer.” The CDC identifies hand washing as the “single most important infection control measure.” When soap and water aren’t available, use alcohol-based hand sanitizer containing at least 60% alcohol. The bathroom represents a critical moment to maintain hygiene before boarding, as Dr. Marina Gafanovich, a New York-based primary care physician, notes. Research confirms that airplane lavatories harbor significant germs on sinks, flush handles, and toilet seats, making paper towel use essential when touching these surfaces.

High-Touch Surfaces

The flu virus survives on hard airplane surfaces for up to 24 hours, meaning tray tables, overhead air vents, lavatory buttons, and seat belt buckles present ongoing transmission risk. “Don’t use the tray table and, if you really have to, make sure you carry sanitary wipes with you and clean it before you use it,” said Gafanovich. She also recommends avoiding the seatback pocket, where many travelers store items, creating a germ reservoir. Dr. Testa recommends wiping down air vents, flush buttons, and seat belt buckles before contact.

The Face-Touch Rule

Keeping hands away from your face is equally critical. According to Dr. Frank Contacessa, a Florida-based internist, “Even if your hands have touched the dirtiest, germiest surfaces, you won’t get sick from that unless you bring those germs to a point of entry (nose, mouth, eyes).” Avoid rubbing your eyes, touching your mouth, or touching your nose unless you’ve just washed your hands. Dr. Julie Fischer, an associate research professor in microbiology and immunology at Georgetown University, notes that gloves can help by creating awareness of this habit, though careful hand washing remains the best protection.

The Airplane Environment

Humidity and Dehydration

Airplane cabins maintain humidity levels of only 10% to 20%, according to Northwestern Medicine. This is well below the 30% to 65% range considered comfortable indoors, and the low moisture dries out mucous membranes in your nose and airways, making them more vulnerable to viruses and bacteria. Staying hydrated counteracts this effect. Dr. Nate Favini, chief medical officer at Pair Team, a virtual care company, recommends drinking eight ounces of water per hour in the air. Alcohol and caffeine worsen dehydration, so reserve those beverages for your destination.

Ventilation and Filtration

Contrary to intuition, keeping your overhead air vent on may actually improve your protection. “There’s been some research that showed that using the overhead air vent, directed straight downward, can create a cone of protection,” said Contacessa. “The airflow from the vent can help to ward off another passenger’s sneeze germs.” Airplane HEPA filters remove at least 99.97% of airborne viruses and bacteria, and the cabin air is refreshed approximately 20 times per hour, compared to roughly 10 times in a typical office building.

Seat Selection

Choosing where you sit affects your illness exposure. Aisle seats experience significantly more traffic, and sick passengers often brace themselves on these seats when walking to the bathroom. “The window seat is a better selection if you want to minimize the risk of respiratory transmission,” said Testa. Window seats generate less contact with other passengers and offer a marginal but measurable advantage for health protection.

Pre-Flight Preparation

Vaccination Strategy

Before boarding, the CDC recommends staying current on vaccinations, including annual flu shots, COVID-19 boosters, and RSV vaccines for those who are eligible. These prevent or reduce the severity of illness. Prioritizing these doses before holiday travel is more effective than any in-flight measure.

Immune Support and Supplements

Beyond vaccines, lifestyle measures strengthen your immune system. According to Dr. Bhatia, “Prioritize sleep, a balanced diet, and supplements like vitamin D and zinc.” Dr. Favini adds that vitamin C offers particular value during stressful travel: “Studies have shown that people under stress who take 1,000 milligrams of vitamin C per day are less likely to fall ill with viral infections.” Travel itself creates physiological stress, making supplementation worthwhile.

Practical Protection Checklist

Stock your travel bag with alcohol-based hand sanitizer wipes, paper towels, and your chosen supplements before departure. When it comes time to purchase these items, some credit cards earn bonus points at drugstores or grocery stores, and certain cards offer rewards on medical expenses, according to The Points Guy. The most effective approach combines vaccination, hydration, hand hygiene, smart seating, and supplement support, reducing your illness risk and protecting those around you during flu season.

Source: The Points Guy Articles

Frequently Asked Questions

Should I wear a mask on a plane?

Though mask mandates have ended, the CDC recommends masks for sick travelers with fever or respiratory symptoms, and for those sitting near symptomatic passengers. A 2020 study by the U.S. Department of Defense found COVID-19 transmission on planes was "extremely unlikely" when masks were worn, and masks also block influenza and other respiratory viruses transmitted through the air.

What's the best seat to choose on a plane to minimize illness risk?

Window seats are preferable to aisle seats because they experience less traffic and contact with other passengers. According to medical experts, aisle seats run a greater risk of exposure since sick passengers often brace themselves on these seats when walking to the bathroom.

How much water should I drink on a plane to stay healthy?

Aim to drink eight ounces of water per hour you're in the air, as airplane cabins maintain only 10-20% humidity compared to the comfortable 30-65% range indoors. Avoid alcohol and caffeine, which worsen dehydration rather than help it.

Written by
Sophie Bennett

Sophie Bennett is a mother of two who writes about family travel — choosing the right accommodation, packing smart, and keeping kids entertained on long flights. She tests every tip before recommending it to readers.